with the rapid development of science and technology, the economic and social requirements for the ability of talents are becoming higher and higher. Project-based learning is a kind of project-oriented learning. In junior middle school chemistry teaching, the introduction of project-based learning can not only stimulate students’ interest in learning, but also help students understand and apply chemical knowledge better. This research discusses the application of project-based learning in chemistry teaching in junior high school by taking the self-made simple oxygen-making machine as an example.