Teaching laboratory has become an important place to carry out classroom teaching and scientific research in colleges and universities and is also the front position of training high-level talents in colleges and universities. The safety management of university teaching laboratory is the focus of the safety management of education system because of its complicated content and heavy safety responsibility. The insufficiency of domestic colleges and universities teaching laboratory safety management, the research has on the implementation of laboratory safety management system in colleges and universities at home and abroad, and strategic planning and management of laboratory safety forward-looking layout, make early warning, prevention and control of laboratory safety accident prediction mechanism, accurately capture hazards information, strengthen the college laboratory safety management innovation ability, improve the management level, To maintain the safety and stability of the campus and protect the lives of teachers and students, pay attention to the protection of the environment and occupational health, and study the implementation of the EHS safety management system in university teaching laboratory can be the focus of our work in the future.