Aiming at the problem that the toxic by-product sulfur dioxide is easily generated in the experiment of "Cothermal Reaction of Iron and Sulfur" in the Chemical Compulsory Ⅱ for senior high school of PEP, a green integrated experiment was designed and fabricated, which can not only complete the cothermal reaction of iron and sulfur but also complete the exploration experiment of sulfur dioxide properties and exhaust gas treatment operation. The experimental design converted the toxic experimental by-product sulfur dioxide into usable classroom teaching resources.The experimental design equipment is easy to obtain, simple to operate, and the experimental effect is obvious.The core literacy of the chemistry subject of "scientific inquiry and innovation consciousness" advocated by the new curriculum standard has been implemented.